Champions Oncology (CSBR) risk factors, FY2025 10-K

Champions Oncology's FY2025 10-K, filed Jul 23, 2025, lists 31 risk factors. There is no earlier 10-K to compare against, so the most company-specific risks are listed below.

Risk factors listed
310 groups
Section length
6k wordsItem 1A

Champions Oncology's biggest risks in the FY2025 10-K

  • Champions Oncology relies primarily on research services and a single Rockville laboratory facility containing its mouse colony and TumorBank.
  • The company faces high competition, customer study cancellations, and operational risks tied to management in Israel.

The risks most specific to Champions Oncology

  • Our laboratories are subject to regulation and licensure requirements, and the healthcare industry is highly regulated; we may face substantial penalties, and our business activities may be impacted, if we fail to comply

    Our research services are performed in Rockville laboratories that are subject to state regulation and healthcare industry licensure requirements.

  • If our laboratory facilities are damaged or destroyed, or we have a dispute with one of our landlords, our business would be negatively affected

    If our leased laboratory facility in Rockville, Maryland is damaged, we could lose ongoing drug studies and our TumorBank.

  • Any health crisis impacting our colony of laboratory mice could have a negative impact on our business

    A health crisis or pathogen affecting our live mouse colony would disrupt our research services and force us to repeat studies.

  • Research service studies are subject to cancellation based on changes in customer’s development plans

    Pharmaceutical and biotechnology customers may cancel research service studies based on changes to their development plans or budgets.

  • We face competition in the life science market for computational software and for bioinformatics products

    We face competition in the life science market for our computational software platform from other providers and open-source communities.

  • Our management and four significant stockholders collectively own a substantial majority of our common stock

    Our officers, directors, and three significant stockholders own approximately 72% of our outstanding common stock as of July 21, 2025.

  • Our Chief Executive Officer resides in Israel and we have several customers with their operations located in Israel, and, therefore, our leadership continuity and results may be adversely affected by political, economic, and military instability in Israel

    Our Chief Executive Officer resides in Israel and several customers operate there, exposing us to regional political, economic, and military instability.

All 31 risk factors

Headings as the filing states them, in filing order.

Other

  1. 01We historically incurred losses from operating activities, may require significant capital and may never achieve sustained profitability
  2. 02Currently, the Company derives revenue primarily from research services, while pursuing efforts to further develop our drug discovery business units
  3. 03We may incur greater costs than anticipated, which could result in sustained losses
  4. 04We may not be able to implement our business strategies, which could impair our ability to continue operations
  5. 05Our laboratories are subject to regulation and licensure requirements, and the healthcare industry is highly regulated; we may face substantial penalties, and our business activities may be impacted, if we fail to comply
  6. 06If our laboratory facilities are damaged or destroyed, or we have a dispute with one of our landlords, our business would be negatively affected
  7. 07Any health crisis impacting our colony of laboratory mice could have a negative impact on our business
  8. 08We have limited experience marketing and selling our products and may need to rely on third parties to successfully market and sell our products and generate revenues
  9. 09We will continue to be dependent upon key employees
  10. 10Because our industry is very competitive and many of our competitors have substantially greater capital resources and more experience in research and development, we may not succeed in selling or increasing sales of our products and technologies
  11. 11If we are unable to protect our intellectual property, we may not be able to compete as effectively
  12. 12If we are unable to protect the confidentiality of our trade secrets, our business and competitive position would be harmed
  13. 13Claims by others that our products infringe their patents or other intellectual property rights could adversely affect our financial condition
  14. 14Research service studies are subject to cancellation based on changes in customer’s development plans
  15. 15We face competition in the life science market for computational software and for bioinformatics products
  16. 16Drug development programs, particularly those in early stages of development, may never be commercialized
  17. 17Impairment of goodwill may adversely impact future results of operations
  18. 18Our ability to use our net operating loss carry-forwards and certain other tax attributes may be limited
  19. 19We have a limited market for our common stock, which makes our securities very speculative
  20. 20Investment in our common stock may be diluted if we issue additional shares in the future
  21. 21Potential future sales or issuances of our common stock to raise capital, or the perception that such sales could occur, could cause dilution to our current stockholders and the price of our common stock to fall
  22. 22Our stock price is volatile and therefore investors may not be able to sell their common stock at or above the price they paid for it
  23. 23Certain provisions of our charter and bylaws and of our contractual agreements contain provisions that could delay and discourage takeover attempts and any attempts to replace our current management by stockholders
  24. 24Certain provisions of Delaware law make it more difficult for a third party to acquire us and make a takeover more difficult to complete, even if such a transaction were in the stockholders’ interest
  25. 25Our management and four significant stockholders collectively own a substantial majority of our common stock
  26. 26We have not paid any cash dividends in the past and have no plans to issue cash dividends in the future, which could cause the value of our common stock to have a lower value than other similar companies which do pay cash dividends
  27. 27If securities or industry analysts do not publish or cease publishing research or reports about us, our business or our market, or if they change their recommendations regarding our common stock adversely, the price of our common stock and trading volume could decline
  28. 28Our business operations could be disrupted if our information technology systems fail to perform adequately
  29. 29A pandemic, epidemic, or outbreak of an infectious disease in the United States or elsewhere may adversely affect our business and we are unable to predict the potential impact
  30. 30Deterioration in general economic conditions in the United States and globally, including the effect of prolonged periods of inflation on our customers and suppliers, could harm our business and results of operations
  31. 31Our Chief Executive Officer resides in Israel and we have several customers with their operations located in Israel, and, therefore, our leadership continuity and results may be adversely affected by political, economic, and military instability in Israel

Other Champions Oncology 10-Ks

  • FY2026 10-K risk factors
    31 risks2 reworded

    Results deteriorated from $4.7 million net income to $1.2 million net loss, with accumulated deficit increasing to $81.1 million.

    Filed Jul 27, 2026

About this page

The headings are the filing's own. The one-line readings and the overview are automated and can be wrong: read Item 1A of the 10-K for the exact wording.