Denali Therapeutics (DNLI) executive compensation, 2026 proxy

Ryan J. Watts, Ph.D., President and Chief Executive Officer, was paid $4.8M in 2025, down 28% from $6.6M the year before. The CEO-to-median-employee pay ratio was 13:1, on median employee pay of $370,857.

Filed
April 21, 2026
Annual meeting
June 3, 2026
Pay year
2025
Named executives
3
CEO total pay
$4.8M-28% vs prior year
CEO to median employee
13:1median $370,857
CEO pay in equity
70%$3.3M in awards
Prior say-on-pay support
91%of votes cast
CEO Target Bonus
65%Of annual base salary
Say-on-Pay Support
90.5%From 2025 annual meeting
Median Employee Pay
$370,857For fiscal year 2025
CEO Pay Ratio
12.8:1Ratio to median employee

How Ph.D. was paid

$4.8M in total for 2025, as reported in the Summary Compensation Table. Equity awards are valued at grant, not at what they turned out to be worth.

Salary15%Bonus14%Stock awards24%Option awards46%All other compensation1%

Named executive officers

ExecutiveTotal
Ryan J. Watts, Ph.D.President and Chief Executive Officer$4,751,515
Alexander O. Schuth, M.D.Chief Operating and Financial Officer and Secretary$4,258,045
Carole Ho, M.D.Chief Medical Officer and Head of Development$3,828,870

What changed and why

  • $4.8MCEO total compensation decreased to $4,751,515 in fiscal 2025 from $6,557,662 in fiscal 2024.
  • $718KDr. Watts received a base salary of $718,000 for fiscal 2025.
  • Stock and option awards for executives consisted of time-based RSUs and stock options.
  • Dr. Ho resigned as Chief Medical Officer and Head of Development on November 14, 2025.
  • 90.5%The 2025 advisory say-on-pay vote received approximately 90.5% support from stockholders.

About this page

Figures are automated and can be wrong; check the filing for the exact numbers. Totals follow SEC rules, which value stock and option awards at grant. Read the DEF 14A proxy statement for footnotes and the compensation committee's full reasoning.