Prime Medicine (PRME) executive compensation, 2026 proxy

Allan Reine, M.D., Chief Executive Officer, was paid $3.9M in 2025, down 16% from $4.6M the year before.

Filed
April 23, 2026
Annual meeting
June 5, 2026
Pay year
2025
Named executives
4
CEO total pay
$3.9M-16% vs prior year
CEO Target Bonus
60%Percentage of annual base salary
CTO Bonus Payout
120%Percentage of target

How M.D. was paid

$3.9M in total for 2025, as reported in the Summary Compensation Table. Equity awards are valued at grant, not at what they turned out to be worth.

Salary16%Option awards73%Non-equity incentive10%All other compensation1%

Named executive officers

ExecutiveTotal
Allan Reine, M.D.Chief Executive Officer$3,894,187
Keith Gottesdiener, M.D.Former Chief Executive Officer$2,207,770
Ann Lee, Ph.D.Chief Technical Officer$1,550,116
Jeremy Duffield, M.D., Ph.D., FRCPFormer Chief Scientific Officer$1,317,797

What changed and why

  • $3.9MAllan Reine total compensation for 2025 was $3,894,187 after becoming Chief Executive Officer in May.
  • Keith Gottesdiener stepped down as Chief Executive Officer in May 2025 and received severance payments.
  • 120%Ann Lee earned an annual cash bonus payout equal to 120% of target based on corporate achievement.
  • Equity awards granted to executives included both time-based and performance-based stock options.

About this page

Figures are automated and can be wrong; check the filing for the exact numbers. Totals follow SEC rules, which value stock and option awards at grant. Read the DEF 14A proxy statement for footnotes and the compensation committee's full reasoning.