Risk factors

Spruce Biosciences (SPRB) risk factors

Item 1A of every Spruce Biosciences, Inc. 10-K on file, and what changed from one year to the next. Readings are automated and can be wrong; check the filing for the exact wording.

  • FY2025 10-K risk factors
    87 risks15 new14 dropped28 reworded

    Spruce Biosciences faces substantial financial losses and relies heavily on ongoing clinical development of TA-ERT and tildacerfont.

    Filed Mar 09, 2026
  • FY2024 10-K risk factors
    86 risks

    Spruce Biosciences faces substantial going concern doubt with only $38.8 million in cash as of December 31, 2024.

    Filed Apr 15, 2025