Risk factors

Verastem (VSTM) risk factors

Item 1A of every Verastem, Inc. 10-K on file, and what changed from one year to the next. Readings are automated and can be wrong; check the filing for the exact wording.

  • FY2025 10-K risk factors
    67 risks11 new5 dropped13 reworded

    Verastem successfully transitioned to commercializing AVMAPKI FAKZYNJA CO-PACK following accelerated approval for recurrent LGSOC.

    Filed Mar 04, 2026
  • FY2024 10-K risk factors
    61 risks

    Verastem carries heavy financial risk with $955.5 million in accumulated deficit, a new $150.0 million debt facility, and required going concern evaluations. The company faces high regulatory hurdles for clinical trials and commercialization of its lead oncology candidates, avutometinib and defactinib. Reliance on third-party manufacturers, clinical investigators, and licensing partners like Pfizer and Chugai exposes the pipeline to external failures.

    Filed Mar 20, 2025