Risk factors

Ionis Pharmaceuticals (IONS) risk factors

Item 1A of every Ionis Pharmaceuticals Inc. 10-K on file, and what changed from one year to the next. Readings are automated and can be wrong; check the filing for the exact wording.

Open IONS in Gloom →
Ionis Pharmaceuticals' chart, financials and news, free in your browser.Open IONS in Gloom →
  • FY2025 10-K risk factors
    36 risks2 new5 dropped11 reworded

    AI use is newly identified as a business, competitive, legal, regulatory, and reputational risk.

    Filed Feb 26, 2026
  • FY2024 10-K risk factors
    48 risks

    Clinical, regulatory and commercialization failures could prevent medicines from reaching patients or generating revenue.

    Filed Feb 19, 2025