Mckesson (MCK) risk factors, FY2025 10-K

Mckesson's FY2025 10-K, filed May 09, 2025, lists 37 risk factors in 2 groups. There is no earlier 10-K to compare against, so the most company-specific risks are listed below.

Risk factors listed
372 groups
Section length
9k wordsItem 1A

Mckesson's biggest risks in the FY2025 10-K

  • McKesson faces significant legal and regulatory risks tied to the distribution of opioids and pharmaceuticals.
  • The company relies heavily on third-party suppliers, complex IT systems, and government contracts.
  • Compliance with extensive healthcare, data privacy, and anti-corruption laws drives major operational costs.

The risks most specific to Mckesson

  • General Risks

    We experience costly legal disputes, government actions, and adverse publicity regarding our role in distributing controlled substances such as opioids

    The company faces numerous lawsuits and adverse publicity related to its role in distributing controlled substances such as opioids.

  • General Risks

    We experience increased costs to distribute controlled substances such as opioids

    State-level legislation and taxes targeting opioid distribution could increase our operating costs in ways we cannot predict.

  • General Risks

    We might lose our ability to purchase, store, or distribute pharmaceuticals, including controlled substances, and medical products

    We risk losing licenses from the DEA, FDA, and state boards to purchase, store, and distribute pharmaceuticals and controlled substances.

  • General Risks

    We experience cybersecurity incidents that might significantly compromise our technology systems or might result in material data breaches

    Cybersecurity incidents could compromise sensitive health and personal information stored across our technology systems and third-party vendors.

  • General Risks

    We might not realize the expected tax treatment from our split-off of Change Healthcare

    We might not realize the expected tax treatment or benefits from the 2020 split-off of Change Healthcare.

  • General Risks

    We may be unsuccessful in achieving our strategic growth objectives

    Our strategic growth depends on successfully building an integrated oncology and specialty care platform and expanding biopharma services.

  • Industry and Economic Risks

    We are adversely impacted as a result of our distribution of generic pharmaceuticals

    Supply chain disruptions and regulatory challenges can prevent our partners from delivering committed generic pharmaceutical products.

All 37 risk factors

Headings as the filing states them, in filing order.

General Risks

  1. 01We experience costly and disruptive legal disputes
  2. 02We experience losses not covered by insurance or indemnification
  3. 03We experience costly legal disputes, government actions, and adverse publicity regarding our role in distributing controlled substances such as opioids
  4. 04We experience increased costs to distribute controlled substances such as opioids
  5. 05We are subject to extensive, complex, and challenging healthcare, environmental, and other laws
  6. 06We are subject to extensive and frequently changing laws relating to healthcare fraud, waste, and abuse
  7. 07We might lose our ability to purchase, store, or distribute pharmaceuticals, including controlled substances, and medical products
  8. 08Privacy, cybersecurity, data protection, and AI laws increase our compliance burden
  9. 09Anti-bribery and anti-corruption laws increase our compliance burden
  10. 10We might record significant charges from impairment to goodwill, intangibles, and other long-lived assets
  11. 11We experience cybersecurity incidents that might significantly compromise our technology systems or might result in material data breaches
  12. 12We experience significant problems with information systems or networks
  13. 13Our technology products or services might not conform to specifications or perform as we intend
  14. 14Pharmaceutical and medical products that we distribute might not conform to specifications or perform as intended
  15. 15We might not realize expected benefits from business process initiatives
  16. 16We might be unable to successfully complete or integrate acquisitions or other strategic transactions
  17. 17From time to time we are adversely impacted by delays or other difficulties with divestitures
  18. 18We might not realize the expected tax treatment from our split-off of Change Healthcare
  19. 19We might be adversely impacted by outsourcing or similar third-party relationships
  20. 20We may be unsuccessful in achieving our strategic growth objectives
  21. 21We are impacted by customer purchase reductions, contract non-renewals, payment defaults, and bankruptcies
  22. 22Our contracts with governmental entities involve future funding and compliance risks
  23. 23We might be harmed by changes in our relationships or contracts with suppliers
  24. 24We might infringe intellectual property rights or our intellectual property protections might be inadequate
  25. 25Our use of third-party data is subject to risks and limitations that could impede the growth of our data services business
  26. 26We might be unable to successfully recruit and retain qualified employees
  27. 34Conditions and events outside of our control, such as widespread public health issues, natural disasters, and geopolitical factors adversely impact our business operations and our financial position or results of operations
  28. 35We may be adversely affected by global climate change or by regulatory or market responses to such change
  29. 36Evolving expectations and regulatory requirements related to governance and sustainability matters may damage our reputation and have an adverse effect on our business, financial condition, and results of operations
  30. 37Exclusive forum provisions in our Bylaws could limit our stockholders’ ability to choose their preferred judicial forum for disputes with us or our directors, officers, or employees

Industry and Economic Risks

  1. 27We might be adversely impacted by healthcare reform such as changes in pricing and reimbursement models
  2. 28We are adversely impacted by competition and industry consolidation
  3. 29From time to time we have difficulties in sourcing or selling products due to a variety of causes and are adversely impacted by disruptions or changes in product supply
  4. 30We are adversely impacted as a result of our distribution of generic pharmaceuticals
  5. 31We are adversely impacted by changes in the economic environments in which we operate, including from inflation, an economic slowdown, a recession, or fluctuations in foreign currency exchange rates
  6. 32Changes affecting capital and credit markets might impede access to credit, increase borrowing costs, and disrupt banking services for us and our customers and suppliers and might impair the financial soundness of our customers and suppliers
  7. 33We might be adversely impacted by tax legislation or challenges to our tax positions

Other Mckesson 10-Ks

  • FY2026 10-K risk factors
    136 risks136 new37 dropped

    Newly shown content centers on accounting estimates, including $11.3 billion goodwill and $4.1 billion intangible assets.

    Filed May 08, 2026

About this page

The headings are the filing's own. The one-line readings and the overview are automated and can be wrong: read Item 1A of the 10-K for the exact wording.