Mckesson's biggest risks in the FY2025 10-K
- McKesson faces significant legal and regulatory risks tied to the distribution of opioids and pharmaceuticals.
- The company relies heavily on third-party suppliers, complex IT systems, and government contracts.
- Compliance with extensive healthcare, data privacy, and anti-corruption laws drives major operational costs.
The risks most specific to Mckesson
- General Risks
We experience costly legal disputes, government actions, and adverse publicity regarding our role in distributing controlled substances such as opioids
The company faces numerous lawsuits and adverse publicity related to its role in distributing controlled substances such as opioids.
- General Risks
We experience increased costs to distribute controlled substances such as opioids
State-level legislation and taxes targeting opioid distribution could increase our operating costs in ways we cannot predict.
- General Risks
We might lose our ability to purchase, store, or distribute pharmaceuticals, including controlled substances, and medical products
We risk losing licenses from the DEA, FDA, and state boards to purchase, store, and distribute pharmaceuticals and controlled substances.
- General Risks
We experience cybersecurity incidents that might significantly compromise our technology systems or might result in material data breaches
Cybersecurity incidents could compromise sensitive health and personal information stored across our technology systems and third-party vendors.
- General Risks
We might not realize the expected tax treatment from our split-off of Change Healthcare
We might not realize the expected tax treatment or benefits from the 2020 split-off of Change Healthcare.
- General Risks
We may be unsuccessful in achieving our strategic growth objectives
Our strategic growth depends on successfully building an integrated oncology and specialty care platform and expanding biopharma services.
- Industry and Economic Risks
We are adversely impacted as a result of our distribution of generic pharmaceuticals
Supply chain disruptions and regulatory challenges can prevent our partners from delivering committed generic pharmaceutical products.
All 37 risk factors
Headings as the filing states them, in filing order.
General Risks
- 01We experience costly and disruptive legal disputes
- 02We experience losses not covered by insurance or indemnification
- 03We experience costly legal disputes, government actions, and adverse publicity regarding our role in distributing controlled substances such as opioids
- 04We experience increased costs to distribute controlled substances such as opioids
- 05We are subject to extensive, complex, and challenging healthcare, environmental, and other laws
- 06We are subject to extensive and frequently changing laws relating to healthcare fraud, waste, and abuse
- 07We might lose our ability to purchase, store, or distribute pharmaceuticals, including controlled substances, and medical products
- 08Privacy, cybersecurity, data protection, and AI laws increase our compliance burden
- 09Anti-bribery and anti-corruption laws increase our compliance burden
- 10We might record significant charges from impairment to goodwill, intangibles, and other long-lived assets
- 11We experience cybersecurity incidents that might significantly compromise our technology systems or might result in material data breaches
- 12We experience significant problems with information systems or networks
- 13Our technology products or services might not conform to specifications or perform as we intend
- 14Pharmaceutical and medical products that we distribute might not conform to specifications or perform as intended
- 15We might not realize expected benefits from business process initiatives
- 16We might be unable to successfully complete or integrate acquisitions or other strategic transactions
- 17From time to time we are adversely impacted by delays or other difficulties with divestitures
- 18We might not realize the expected tax treatment from our split-off of Change Healthcare
- 19We might be adversely impacted by outsourcing or similar third-party relationships
- 20We may be unsuccessful in achieving our strategic growth objectives
- 21We are impacted by customer purchase reductions, contract non-renewals, payment defaults, and bankruptcies
- 22Our contracts with governmental entities involve future funding and compliance risks
- 23We might be harmed by changes in our relationships or contracts with suppliers
- 24We might infringe intellectual property rights or our intellectual property protections might be inadequate
- 25Our use of third-party data is subject to risks and limitations that could impede the growth of our data services business
- 26We might be unable to successfully recruit and retain qualified employees
- 34Conditions and events outside of our control, such as widespread public health issues, natural disasters, and geopolitical factors adversely impact our business operations and our financial position or results of operations
- 35We may be adversely affected by global climate change or by regulatory or market responses to such change
- 36Evolving expectations and regulatory requirements related to governance and sustainability matters may damage our reputation and have an adverse effect on our business, financial condition, and results of operations
- 37Exclusive forum provisions in our Bylaws could limit our stockholders’ ability to choose their preferred judicial forum for disputes with us or our directors, officers, or employees
Industry and Economic Risks
- 27We might be adversely impacted by healthcare reform such as changes in pricing and reimbursement models
- 28We are adversely impacted by competition and industry consolidation
- 29From time to time we have difficulties in sourcing or selling products due to a variety of causes and are adversely impacted by disruptions or changes in product supply
- 30We are adversely impacted as a result of our distribution of generic pharmaceuticals
- 31We are adversely impacted by changes in the economic environments in which we operate, including from inflation, an economic slowdown, a recession, or fluctuations in foreign currency exchange rates
- 32Changes affecting capital and credit markets might impede access to credit, increase borrowing costs, and disrupt banking services for us and our customers and suppliers and might impair the financial soundness of our customers and suppliers
- 33We might be adversely impacted by tax legislation or challenges to our tax positions
Other Mckesson 10-Ks
- FY2026 10-K risk factors136 risks136 new37 dropped
Newly shown content centers on accounting estimates, including $11.3 billion goodwill and $4.1 billion intangible assets.
Filed May 08, 2026
About this page
The headings are the filing's own. The one-line readings and the overview are automated and can be wrong: read Item 1A of the 10-K for the exact wording.